Recovery and purification of biopharmaceuticals are important steps that have a great impact on product quality and manufacturing costs. We at EUGENEX Biotechnologies offer downstream process development and optimization customized for the unique characteristics of the desired protein. This includes removal of residual DNA, host cell proteins, and removal of potential viruses. With our broad expertise in the systematic purification of monoclonal antibodies, fusion proteins, and other biopharmaceuticals, we are able to remove impurities and increase yields with minimal steps to facilitate a cost-efficient manufacturing.
- Clarification of harvest by different techniques
- Product isolation and purification using various chromatography techniques
- Product polishing
- Downscaling for virus studies and analytic purposes
- Scale-up and contract manufacturing of biologicals under non-GMP conditions up to kg scale
- Process accompanying analytics and assays for protein characterization
- Technology transfer including demonstration and training